SMAT Platform

   References

• Hu, W., Bürli, R.W., Kaizerman, J.A., Johnson, K.W., Gross, M.I., Iwamoto, M., Jones, P., Lofland, D., Difuntorum, S., Chen, H., Bozdogan, B., Appelbaum, P.C., and Moser, H.E. (2004)
  
  DNA Binding Ligands with Improved in Vitro and in Vivo Potency against Drug-Resistant Staphylococcus aureus.
  J. Med. Chem. 47: 4352-4355
  
  
  
• Bürli, R.W., Kaizerman, J.A., Duan, J., Jones, P., Johnson, K.W., Iwamoto, M., Truong, K., Hu, W., Stanton, T., Chen, A., Touami, S., Gross, M., Jiang, V., Ge, Y., and Moser, H.E. (2004)
  
  DNA Binding Ligands with in Vivo Efficacy in Murine Models of Bacterial Infection: Optimization of Internal Aromatic Amino Acids.
  Bioorg. Med. Chem. Lett. 14: 2067-2072.
  
  
  
• Bürli, R.W., McMinn, D., Kaizerman, J.A., Hu, W., Ge, Y., Pack, Q., Jiang, V., Gross, M., Garcia, M., Tanaka, R., and Moser, H.E. (2004)
  
  DNA Binding Ligands Targeting Drug-Resistant Gram-Positive Bacteria. Part I: Internal Benzimidazole Derivatives.
  Bioorg. Med. Chem. Lett. 14: 1253-1257.
  
  
  
• Bürli, R.W., Jones, P., McMinn, D., Le, Q., Duan, J., Kaizerman, J.A., Difuntorum, S., and Moser, H.E. (2004)
  
  DNA Binding Ligands Targeting Drug-Resistant Gram-Positive Bacteria. Part 2: C-terminal Benzimidazoles and Derivatives.
  Bioorg. Med. Chem. Lett. 14: 1259-1263.
  
  
  
• Gross, M., Bürli, R., Jones, P., Garcia, M., Batiste, B., Kaizerman, J., Moser, H., Jiang, V., Hoch, U., Duan, J., Tanaka, R., and Johnson, K.W. (2003)
  
  Pharmacology of Novel Heteroaromatic Polycycle Antibacterials.
  Antimicrob. Agents Chemother. 47: 3448-3457.
  
  
  
• Kaizerman, J.A., Gross, M.I., Ge, Y., White, S., Hu, W., Duan, J., Baird, E.E., Johnson, K.W., Tanaka, R.D., Moser, H.E., and Bürli, R.W. (2003)
  
  DNA Binding Ligands Targeting Drug-Resistant Bacteria: Structure, Activity, and Pharmacology.
  J. Med. Chem. 46:3914-3929.
  
  
  
• Ge, Y., Difuntorum, S., Touami, S., Critchley, I., Bürli, R.W., Jiang, V., Drazan, K., and Moser, H.E. (2002)
  
  In Vitro Antimicrobial Activity of GSQ1530, a New Heteroaromatic Polycyclic Compound.
  Antimicrob. Agents Chemother. 46: 3168-3174.
  
  
  
• Bürli, R.W., Ge, Y., White, S., Baird, E.E., Touami, S.M., Taylor, M., Kaizerman, J.A., and Moser, H.E. (2002)
  
  DNA Binding Ligands with Excellent Antibiotic Potency Against Drug-Resistant Gram-Positive Bacteria.
  Bioorg. Med. Chem. Lett. 12: 2591-2594.